WoundPath™ & NailPath™

WoundPath™ & NailPath™

Human skin plays a vital role in preventing microbes from entering the body. Any open skin wound due to accidental cuts, animal bites, blisters, surgical or other issues are quickly colonized by several different highly pathogenic microorganisms both bacterial (Clostridium, Enterobacter, Pseudomonas and Staphylococcus) and fungal (Candida) species.

In addition, battle injuries suffered by military personnel as well as civilian firearm injuries are often severe and may take extensive time to heal thereby requiring prolonged hospitalization. This creates an opportunity for bacterial and fungal pathogens to infect the wounds associated with such injuries.

Despite the usage of antibiotics, microbes can easily penetrate the skin through wounds or infections, attack the underlying tissue and eventually get into the blood stream. This could lead to sepsis, trauma or ultimately amputation.

Nails are vulnerable to fungal (Trichophyton) and bacterial (Pseudomonas and Staphylococcus) infections. Immunocompromised patients and patients with diabetic or heart conditions are highly vulnerable to skin wound or toe-nail infections.

Patients’ specimens for WoundPath™ and NailPath™ arrive daily from surgery centers, dermatology clinics, and podiatric facilities. NCF Diagnostics & DNA Technologies has processed over 50,000 wound and nail specimens using Real-Time PCR to identify microbial pathogens.

WoundPath™ and NailPath™ test kits can be ordered by contacting our laboratory staff at 352-375-5553 or supply@ncfdna.com. Within hours, the infected tissue or nail samples can be shipped for microbial analysis and precise identification.

WoundPath™ screens for more than 22 different pathogens that may prevent wounds from healing, including:

Bacteria: 1. Acinetobacter baumannii, 2. Clostridium perfringens, 3. Clostridium tetanii, 4. Corynebacter amycolatum, 5. Corynebacter straitum, 6. Enterococcus faecalis, 7. Enterococcus faecium, 8. Escherichia coli, 9. Klebsiella pneumoniae, 10. Morganella morganii, 11. Proteus mirablis, 12. Pseudomonas aeruginosa, 13. Salmonella enterica, 14. Serratia marcescens, 15. Staphylococcus aureus, 16. Staphylococcus epidermidis, 17. Streptococcus agalactiae & 18. Streptococcus pneumoniae.

Fungi: 1. Candida albicans, 2. Candida glabrata, 3. Candida parapsilosis & 4. Candida tropicalis.

ResistantPath: 1. mecA, 2. mcr-1, 3. tetM, 4. tetS, 5. vanA, 6. vanB & 7. sul1

NailPath™ screens for 22 nail-related pathogens that may be the cause of the fungal growth:

Fungi: 1. Xenoacrimonium recifei, 2. Acremonium strictum, 3. Alternaria alternata, 4. Candida albicans, 5. Candida glabrata, 6. Candida parapsilosis & 7. Candida tropicalis, 8. Cladosporium carrionii, 9. Epidermophyton floccosum, 10. Microsporum canis, 11. Scopulariopsis brevicaulis, 12. Trichophyton mentagraphytes var. interdigitales, 13. Trichophyton metagraphytes var. mentagraphytes, 14. Trichophyton rubrum, 15. Trichophyton schoenleinii, 16. Trichophyton soudanense, 17. Trichophyton tonsurans, 18. Trichophyton verrucosum & 19. Trichophyton violaceum.

Bacteria: 1. Klebsiella pneumoniae, 2. Pseudomonas aeruginosa & 3. Staphylococcus aureus.

ResistantPath: 1. mecA, 2. mcr-1, 3. tetM, 4. tetS, 5. vanA, 6. vanB & 7. sul1