The common cold makes up most cases of acute sinusitis which typically resolves itself within 10 days. Sinusitis becomes chronic when it lasts longer than 12 weeks in spite of medical treatment which means there’s a greater chance of an infection present.
SinoPath™ (Multiplex Sinus RT-PCR Pathogen Panel Testing)
SinoPath was created with ENTs in mind to help diagnose patients suffering from chronic and/ or severe cases of sinusitis. Although respiratory and sinus infections can present similar symptoms, sinusitis can also cause earaches, ear pressure, loss of hearing, facial pain, and balance issues, which are not as common with respiratory illnesses. In these cases, SinoPath is the preferred testing method of detection because the inner ears are swabbed for potential pathogens instead of the throat.
Our RT-PCR SinoPath™ panel is critical in saving time in the diagnosis and treatment processes. As several pathogens from our large molecular diagnostic testing menu are tested all at once, specimen samples are resulted 6-8 hours from when our lab receives the specimen and the identification of antibiotic resistance genes allows physicians to practice precision medicine by giving the relevant data needed for prescribing the correct medication for that specific infection.
Antibiotic prescriptions for patients suffering from C. diff pathogen with toxin A/B or Vibrio chloerae with toxin CtxA lead to pathogen cell explosion and catastrophic toxin release.
Clinical Relevance & Advantages:
- Prevents delays in diagnosis & treatment (6-8 hrs from lab arrival)
- Tests for bacterial, and viral pathogens
- Reduces the spread of infection
- Detects polymicrobial infections simultaneously
- Identifies antibiotic-resistant genes
- Allows for precision medicine through narrow-spectrum antibiotics
- Limits unnecessary exposure to broad-spectrum antibiotics
- Unaffected by the use of current medications such as antibiotics
- Cost savings from earlier diagnosis
SinoPath™ can comprehensively test for 38 potential viral, fungal or bacterial pathogens all at once, including:
Viruses: 1. Flu-A, 2. Flu-H1, 3. Flu-3, Flu-H3, 4. Flu-B, 5. RSV-A, 5. RSV- B
Bacteria: 1. Acinetobacter baumannii, 2. Actinomyces spp., 3. Alloiococcus otitis, 4. Bacteroides fragilis, 5. Chlamydia pneumoniae, 6. Citrobacter freundii, 7. Escherichia coli, 8. Fusobacterium necrophorum, 9. Haemophilus influenzae, 10. Klebsiella pneumoniae, 11. Moraxella catarrhalis,12. Mycoplasma pneumoniae, 13. Peptostreptococcus anaerobius, 14. Prevotella bivia, 16. Pseudomonas aeruginosa, 17. Staphylococcus aureus, 18. Staphylococcus epidermidis, 19. Stenotrophomonas maltophilia, 20. Streptococcus dysgalactiae, 21. Streptococcus pneumoniae, 22. Streptococcus pyogenes
Fungi: 1. Alternaria alternata, 2. Aspergillus fumigatus, 3. Aspergillus niger, 4. Aureobasidium pullulans, 5. Candida albicans, 6. Cladosporium spp., 7. Epicoccum nigrum, 8. Fusarium oxysporum, 9. Helminthosporium, 10. Mucor, 11. Penicillium chrysogenum
ResistantPath: 1. mecA, 2. mcr-1, 3. tetM 4. tetS, 5. vanA, 6. vanB, 7. sul1